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The 2025 recipient of the American Society for Investigative Pathology (ASIP) Rous-Whipple Award is Dr. Anindya Dutta, Endowed Professor and Chair of the Department of Genetics at the University of Alabama – Birmingham (Birmingham, AL).
The ASIP Rous-Whipple Award is presented to a senior scientist with a distinguished career in research who has advanced the understanding of disease and has continued productivity at the time of the award, including impactful science, teaching, mentorship, leadership in the field of pathology, and contributions to the Society.
Dr. Dutta is an internationally recognized leader in the control of genome stability in normal and transformed cells. His discovery of the essential role of geminin in preventing over-replication of DNA, published in Science in 2000, is a landmark in the field. These studies led to the identification of additional factors that prevent over-replication, the DNA damage pathways activated by the over-replication, and the recognition of the mechanism by which Pevonedistat exerts its anti-cancer effect.
Dr. Dutta’s laboratory has made seminal contributions to the understanding of genome instability, including the identification of extrachromosomal circles of DNA (eccDNA) in normal and cancer cells and demonstrating that the circles from cancers are released into the blood and can be exploited as a biomarker.
Dr. Dutta’s research group discovered a novel family of short RNAs, tRFs (or tsRNAs) that have since been implicated in viral pathogenesis and dysregulation of gene expression in cancers, and studied several long noncoding RNAs, including DRAIC and LINC00152, that have a significant role in regulating the pathologic phenotypes of cancer cells.
Dr. Dutta is author on 215 publications. He has contributed to the best pathology journals, including The American Journal of Pathology. He has received over 33 million dollars in grant funding mostly as PI, and currently is the principal investigator on 2 active NIH R01 grants.
Dr. Dutta has been an active member of the ASIP for over 25 years, contributing to the Society with meaningful service and leadership. He has been a Chair and/or organizer of ASIP sessions and symposia at 4 national meetings on the topics of cell cycle, cell growth and differentiation, and gene regulation. He has also served on the ASIP Program Committee. In 2015, Dr. Dutta received the ASIP Outstanding Investigator Award.
Dr. Dutta earned an MBBS from the University of Madras (India) in 1981. He then completed a residency in medicine at Christian Medical College Hospital (Vellore, India). Dr. Dutta subsequently earned a PhD from The Rockefeller University (New York, NY) in 1989.
With a distinguished career, in 2021, Dr. Dutta moved to The University of Alabama – Birmingham to become Endowed Professor and Chair of the Department of Genetics, where he continues to serve.
Dr. Anindya Dutta will receive the 2025 ASIP Rous-Whipple Award during the 2025 Annual Meeting of the ASIP in Portland, OR (April 2025).
